Journal of Neurology, Neurosurgery and Psychiatry

is a leading international journal publishing the latest research and reviews on all areas of neurological sciences.

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Cognitive and neuropsychiatric effects of noradrenergic treatment in Alzheimer’s disease

Repurposing of established noradrenergic drugs is most likely to offer effective treatment in Alzheimer’s disease for general cognition and apathy. However, several factors should be considered before designing future clinical trials. These include targeting of appropriate patient subgroups and understanding the dose effects of individual drugs and their interactions with other treatments to minimise risks and maximise therapeutic effects.

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